Anti-Human CTGF/CCN2 Reference Antibody (Pamrevlumab, RUO)
- Catalog number: BS10053
- Availability: In Stock
$176.00
- Ex Tax: $176.00
Description: Research Grade Pamrevlumab (BS10053) is a human monoclonal antibody detecting IGFBP8 in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human.
Highlights:
• Multi-Application — Validated across multiple applications.
Host species: Human
Isotype: IgG1-kappa
Species reactivity: Human
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 4.35mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: IGFBP8,IGF-bindingprotein8,IBP-8,CTGF,HCS24,CCNfamilymember2,CCN2,Cellularcommunicationnetworkfactor2,Hypertrophicchondrocyte-specificprotein24,Connectivetissuegrowthfactor,Insulin-likegrowthfactor-bindingprotein8,IGFBP-8
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: FG-3019,CAS:946415-13-0
Background: CCN family member 2 (IGFBP8,IGF-binding protein 8,IBP-8,CTGF,HCS24,CCN family member 2,CCN2,Cellular communication network factor 2,Hypertrophic chondrocyte-specific protein 24,Connective tissue growth factor,Insulin-like growth factor-binding protein 8,IGFBP-8) is a ~38 kDa protein. Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Is involved in the stimulation of osteoblast differentiation and has a critical role in osteogenesis. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
References:
1. Li, S. et al. (2024) Bone research 12, 60. PMID: 39414788
Note: For research use only. Not suitable for clinical or therapeutic use.
Highlights:
• Multi-Application — Validated across multiple applications.
Host species: Human
Isotype: IgG1-kappa
Species reactivity: Human
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 4.35mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: IGFBP8,IGF-bindingprotein8,IBP-8,CTGF,HCS24,CCNfamilymember2,CCN2,Cellularcommunicationnetworkfactor2,Hypertrophicchondrocyte-specificprotein24,Connectivetissuegrowthfactor,Insulin-likegrowthfactor-bindingprotein8,IGFBP-8
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: FG-3019,CAS:946415-13-0
Background: CCN family member 2 (IGFBP8,IGF-binding protein 8,IBP-8,CTGF,HCS24,CCN family member 2,CCN2,Cellular communication network factor 2,Hypertrophic chondrocyte-specific protein 24,Connective tissue growth factor,Insulin-like growth factor-binding protein 8,IGFBP-8) is a ~38 kDa protein. Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Is involved in the stimulation of osteoblast differentiation and has a critical role in osteogenesis. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
References:
1. Li, S. et al. (2024) Bone research 12, 60. PMID: 39414788
Note: For research use only. Not suitable for clinical or therapeutic use.
Images
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SDS-PAGESDS-PAGE for Research Grade Pamrevlumab.
