ASFV CD2v/pEP402R/CD2H Recombinant Protein (C-Fc)
- Catalog number: PV10333
- Availability: In Stock
$298.00
- Ex Tax: $298.00
- Description: Recombinant ASFV CD2v/pEP402R/CD2H Protein, C-Fc (PV10333) expressed in Mammalian Cells, spanning Asn17-Thr204. Purity: >90% by SDS-PAGE.
Highlights:
• Fc Fusion — Enhanced stability with Protein A/G purification compatibility.
• Mammalian Expression — Proper folding and native glycosylation.
• High Purity — >90% purity verified by SDS-PAGE. - Form: Lyophilized
- Storage buffer: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
- Purity: >90% as determined by SDS-PAGE.
- Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
- Endotoxin level: Please contact with the lab for this information.
- Expression system: Mammalian Cells
- Protein length: Asn17-Thr204
- Predicted molecular weight: 49.87 kDa
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
- Reconstitution: Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
- Alternative Names: CD2 homolog, CD2H, 5HL, CD2v, T-lymphocyte CD2 receptor-like protein, CD2-like protein, pEP402R, Ba71V-058, EP402R
- Species: African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V) (ASFV)
- Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
- Background: CD2 homolog (CD2v/pEP402R) is a ~45 kDa protein. May play an immunosuppressive role by inhibiting lymphocyte proliferation and subsequently facilitating viral replication and generalization of infection. Responsible for viral hemadsorption, which may help viral spread. Increases virus replication in the tick vector at the step of virus uptake or replication in the tick gut. May play a role in the host Golgi reorganization to yield viral factories. May play a role in host cell penetration.
References:
1. Rodríguez, JM. et al. (1993) Journal of virology 67, 5312-20. PMID: 8102411
2. Ruiz-Gonzalvo, F. et al. (1996) Virology 218, 285-9. PMID: 8615037
3. Rowlands, RJ. et al. (2009) Virology 393, 319-28. PMID: 19729182
4. Pérez-Núñez, D. et al. (2015) PloS one 10, e0123714. PMID: 2591590
5. Yang, S. et al. (2021) Drug delivery 28, 957-962. PMID: 34006158 - Note: For research use only.
Images
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SDS-PAGESDS-PAGE for Recombinant ASFV CD2v/pEP402R/CD2H Protein, C-Fc.
