VSIV G protein/Glycoprotein G Recombinant Protein (C-Strep)

VSIV G protein/Glycoprotein G Recombinant Protein (C-Strep)

  • Catalog number: PV11105
  • Availability: In Stock
  • $298.00

  • Ex Tax: $298.00


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  • Description: Recombinant VSIV G protein/Glycoprotein G Protein, C-Strep (PV11105) expressed in Mammalian Cells. Purity: >90% by SDS-PAGE.
    Highlights:
    • Mammalian Expression — Proper folding and native glycosylation.
    • High Purity — >90% purity verified by SDS-PAGE.
  • Form: Lyophilized
  • Storage buffer: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
  • Purity: >90% as determined by SDS-PAGE.
  • Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
  • Endotoxin level: Please contact with the lab for this information.
  • Expression system: Mammalian Cells
  • Protein length: Lys17-Lys448
  • Predicted molecular weight: 51.40 kDa
  • Stability and Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
  • Reconstitution: Reconstitute in sterile water for a stock solution.
  • Alternative Names: G protein
  • Species: Vesicular stomatitis Indiana virus (VSIV)
  • Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
  • Background: Glycoprotein G is a ~57 kDa protein. Attaches the virus to host LDL receptors, inducing clathrin-dependent endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and endosomal membrane.
    References:
    1. Nikolic, J. et al. (2018) Nature communications 9, 1029. PMID: 29531262
    2. Roche, S. et al. (2006) Science (New York, N.Y.) 313, 187-91. PMID: 16840692
    3. Roche, S. et al. (2007) Science (New York, N.Y.) 315, 843-8. PMID: 17289996
  • Note: For research use only.

Images

  • SDS-PAGE for VSIV G protein/Glycoprotein G Recombinant Protein (C-Strep)
    SDS-PAGE

    SDS-PAGE for Recombinant VSIV G protein/Glycoprotein G Protein, C-Strep.

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