Anti-Human CD39/ENTPD1 Reference Antibody (ES002)
- Catalog number: BS11102
- Availability: In Stock
$370.00
- Ex Tax: $370.00
Description: Anti-Human CD39/ENTPD1 (ES002) (BS11102) is a research-grade recombinant antibody targeting CD39. Produced in mammalian cells with native-like glycosylation.
Highlights:
• Research Grade — For PK/PD studies, assay development, and ADA research.
• Native Glycosylation — Mammalian expression ensures native-like patterns.
Host species: Human
Isotype: IgG4-kappa
Species reactivity: Human
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 1mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: Ecto-ATPdiphosphohydrolase1,NTPDase1,ENTPD1,Ecto-ATPase1,Ecto-apyrase,Ecto-ATPDase1,Ectonucleosidetriphosphatediphosphohydrolase1,CD39,Lymphoidcellactivationantigen
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: ES002
Background: Ectonucleoside triphosphate diphosphohydrolase 1 (CD39/ENTPD1) is a ~57 kDa protein. Catalyzes the hydrolysis of nucleoside triphosphates (NTPs) and diphosphates (NDPs) (Probable). The enzyme sequentially removes phosphate groups in two successive steps, converting NTPs to nucleoside monophosphates (NMPs) via NDP intermediates (Probable). This activity contributes to the regulation of extracellular levels of nucleotides (Probable). By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow.
References:
1. Christoforidis, S. et al. (1995) European journal of biochemistry 234, 66-74. PMID: 852967
2. Wang, TF. et al. (1996) The Journal of biological chemistry 271, 9898-901. PMID: 8626624
3. Kaczmarek, E. et al. (1996) The Journal of biological chemistry 271, 33116-22. PMID: 895516
4. Robson, SC. et al. (1997) The Journal of experimental medicine 185, 153-63. PMID: 8996251
Note: For research use only. Not suitable for clinical or therapeutic use.
Highlights:
• Research Grade — For PK/PD studies, assay development, and ADA research.
• Native Glycosylation — Mammalian expression ensures native-like patterns.
Host species: Human
Isotype: IgG4-kappa
Species reactivity: Human
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 1mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: Ecto-ATPdiphosphohydrolase1,NTPDase1,ENTPD1,Ecto-ATPase1,Ecto-apyrase,Ecto-ATPDase1,Ectonucleosidetriphosphatediphosphohydrolase1,CD39,Lymphoidcellactivationantigen
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: ES002
Background: Ectonucleoside triphosphate diphosphohydrolase 1 (CD39/ENTPD1) is a ~57 kDa protein. Catalyzes the hydrolysis of nucleoside triphosphates (NTPs) and diphosphates (NDPs) (Probable). The enzyme sequentially removes phosphate groups in two successive steps, converting NTPs to nucleoside monophosphates (NMPs) via NDP intermediates (Probable). This activity contributes to the regulation of extracellular levels of nucleotides (Probable). By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow.
References:
1. Christoforidis, S. et al. (1995) European journal of biochemistry 234, 66-74. PMID: 852967
2. Wang, TF. et al. (1996) The Journal of biological chemistry 271, 9898-901. PMID: 8626624
3. Kaczmarek, E. et al. (1996) The Journal of biological chemistry 271, 33116-22. PMID: 895516
4. Robson, SC. et al. (1997) The Journal of experimental medicine 185, 153-63. PMID: 8996251
Note: For research use only. Not suitable for clinical or therapeutic use.
Images
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SDS-PAGESDS-PAGE for Research Grade Anti-Human CD39/ENTPD1 (ES002).
