Anti-MPO Polyclonal Antibody
- Catalog number: PA10281
- Availability: In Stock
$168.00
- Ex Tax: $168.00
- Description: Anti-MPO Polyclonal Antibody (PA10281) is a rabbit polyclonal antibody detecting MPO in ELISA, IHC, WB. Suitable for Human.
Highlights:
• Affinity Purified — Minimal background and high purity for reliable results.
• Multi-Application — Validated across multiple applications. - Host species: Rabbit
- Species reactivity: Human, Mouse, Rat
- Immunogen: E. coli - derived recombinant Human MPO (Val165-Gly278).
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
- Clonality: Polyclonal
- Isotype: IgG
- Applications: ELISA, IHC, WB
- Target: Myeloperoxidase,MPO
- Purification: Purified by antigen affinity column.
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
- Background: Myeloperoxidase (MPO) is a ~83 kDa protein. Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low-density lipoprotein particles and limits vascular damage.
References:
1. Furtmüller, PG. et al. (1998) Biochemistry 37, 17923-30. PMID: 992216
2. Cederlund, M. et al. (2015) Frontiers in physiology 6, 11. PMID: 25698971 - Note: For research use only.
Images
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Western blotWestern blot analysis was performed using anti-MPO polyclonal antibody at 1ug/mL on various samples.
Lane 1: HL-60 cell lysate
Datasheet
