Anti-CD155/PVR Polyclonal Antibody

Anti-CD155/PVR Polyclonal Antibody

  • Catalog number: PA10495
  • Availability: In Stock
  • $168.00

  • Ex Tax: $168.00


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  • Description: Anti-CD155/PVR Polyclonal Antibody (PA10495) is a rabbit polyclonal antibody detecting CD155 in ELISA, IHC, WB. Suitable for Human.
    Highlights:
    • Affinity Purified — Minimal background and high purity for reliable results.
    • Multi-Application — Validated across multiple applications.
  • Host species: Rabbit
  • Species reactivity: Human
  • Immunogen: E. coli - derived recombinant Human CD155/PVR (Trp21-Asn343).
  • Form: Liquid
  • Storage buffer: 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
  • Clonality: Polyclonal
  • Isotype: IgG
  • Applications: ELISA, IHC, WB
  • Target: Nectin-like protein 5,Poliovirus receptor,CD155,PVR,PVS,NECL-5
  • Purification: Purified by antigen affinity column.
  • Stability and Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
  • Background: Poliovirus receptor (CD155/PVR) is a ~45 kDa protein. Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytotoxicity of activated NK cells. May also promote NK cell-target cell modular exchange, and PVR transfer to the NK cell.
  • Note: For research use only.

Images

  • Western blot for Anti-CD155/PVR Polyclonal Antibody
    Western blot

    Western blot analysis was performed using anti-PVR polyclonal antibody at 1μg/ml on various samples.
    Lane 1: Hela cell lysate
    Lane 2: A549 cell lysate
    Lane 3: HUVEC cell lysate
    Lane 4: LO2 cell lysate

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