Anti-CFP Polyclonal Antibody
- Catalog number: PA10641
- Availability: In Stock
$168.00
- Ex Tax: $168.00
- Description: Anti-CFP Polyclonal Antibody (PA10641) is a rabbit polyclonal antibody detecting CFP in ELISA, IHC, WB. Suitable for Human and Pongo abelii.
Highlights:
• Affinity Purified — Minimal background and high purity for reliable results.
• Multi-Application — Validated across multiple applications. - Host species: Rabbit
- Species reactivity: Human
- Immunogen: E. coli - derived recombinant Human CFP (Gln65-Cys190).
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
- Clonality: Polyclonal
- Isotype: IgG
- Applications: ELISA, IHC, WB
- Target: PFC,CFP,Properdin,Complement factor P
- Purification: Purified by antigen affinity column.
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
- Background: Properdin (CFP) is a ~51 kDa protein. A positive regulator of the alternate pathway (AP) of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b).
References:
1. Hourcade, DE. (2006) The Journal of biological chemistry 281, 2128-32. PMID: 16301317
2. Ferreira, VP. et al. (2010) Immunobiology 215, 932-40. PMID: 20382442
3. Pedersen, DV. et al. (2017) The EMBO journal 36, 1084-1099. PMID: 28264884
4. Hourcade, DE. et al. (1998) The Journal of biological chemistry 273, 25996-6000. PMID: 9748277
5. Pedersen, DV. et al. (2019) Frontiers in immunology 10, 2007. PMID: 31507604 - Note: For research use only.
Images
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Western blotWestern blot analysis was performed using anti-CFP polyclonal antibody at 1μg/ml on various samples.
Lane 1: Mouse brain lysate
Lane 2: Rat brain lysate
Datasheet
