Anti-CRMP1 Polyclonal Antibody
- Catalog number: PA11070
- Availability: In Stock
$168.00
- Ex Tax: $168.00
- Description: Anti-CRMP1 Polyclonal Antibody (PA11070) is a rabbit polyclonal antibody detecting CRMP1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights:
• Affinity Purified — Minimal background and high purity for reliable results.
• Multi-Application — Validated across multiple applications.
• Multi-Species — Cross-reactive for translational research. - Host species: Rabbit
- Species reactivity: Human, Mouse, Rat
- Immunogen: E. coli - derived recombinant Human CRMP1 (Met1-Val250).
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
- Clonality: Polyclonal
- Isotype: IgG
- Applications: ELISA, IHC, WB
- Target: ULIP-3,Inactive dihydropyrimidinase,CRMP1,DPYSL1,DRP-1,Dihydropyrimidinase-related protein 1,ULIP3,Collapsin response mediator protein 1,Unc-33-like phosphoprotein 3,CRMP-1
- Purification: Purified by antigen affinity column.
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
- Background: Dihydropyrimidinase-related protein 1 (CRMP1) is a ~62 kDa protein. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance. During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F-actin which results in the rearrangement of the actin cytoskeleton and the collapse of the growth cone. Involved in invasive growth and cell migration. May participate in cytokinesis.
References:
1. Nakamura, F. et al. (2014) Nature communications 5, 5325. PMID: 25358863
2. Shih, JY. et al. (2001) Journal of the National Cancer Institute 93, 1392-400. PMID: 1156239
3. Chen, TC. et al. (2009) Journal of proteome research 8, 4943-53. PMID: 19799413 - Note: For research use only.
Images
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Western blotWestern blot analysis was performed using anti-CEMP1 polyclonal antibody at 1μg/ml on various samples.
Lane 1: Mouse brain lysate
Lane 2: Mouse Cerebellum lysate
Lane 3: Rat brain lysate
Lane 4: Rat Cerebellum lysate
Datasheet
