Anti-Human Gal-1/LGALS1 Polyclonal Antibody
- Catalog number: PA11672
- Availability: In Stock
$168.00
- Ex Tax: $168.00
- Description: Anti-Human Gal-1/LGALS1 Polyclonal Antibody (PA11672) is a rabbit polyclonal antibody detecting LGALS1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Bubalus bubalis.
Highlights:
• Affinity Purified — Minimal background and high purity for reliable results.
• Multi-Application — Validated across multiple applications.
• Multi-Species — Cross-reactive for translational research. - Host species: Rabbit
- Species reactivity: Human
- Immunogen: E. coli - derived recombinant Human Gal-1/LGALS1 (Met1-Asp135).
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
- Clonality: Polyclonal
- Isotype: IgG
- Applications: ELISA, IHC, WB
- Target: HLBP14, Lactose-binding lectin 1, LGALS1, HBL, HPL, Beta-galactoside-binding lectin L-14-I, Gal-1, Lectin galactoside-binding soluble 1, Putative MAPK-activating protein PM12, S-Lac lectin 1, Galaptin, Galectin-1, 14 kDa laminin-binding protein, 14 kDa lectin
- Purification: Purified by antigen affinity column.
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
- Background: Galectin-1 (Gal-1) is a ~14 kDa protein. Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. Plays a negative role in Th17 cell differentiation via activation of the receptor CD69.
References:
1. de la Fuente, H. et al. (2014) Molecular and cellular biology 34, 2479-87. PMID: 24752896 - Note: For research use only.
Images
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Western blotWestern blot analysis was performed using anti-Galectin-1 polyclonal antibody at 1μg/ml on various samples.
Lane 1: NIH3T3 cell lysate
Lane 2: PC-12 cell lysate
Lane 3: LO2 cell lysate
Lane 4: U2OS cell lysate
Lane 5: HCT116 cell lysate
