Anti-Human PRDX1 Polyclonal Antibody
- Catalog number: PA11853
- Availability: In Stock
$168.00
- Ex Tax: $168.00
- Description: Anti-Human PRDX1 Polyclonal Antibody (PA11853) is a rabbit polyclonal antibody detecting PRDX1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Cricetulus griseus.
Highlights:
• Affinity Purified — Minimal background and high purity for reliable results.
• Multi-Application — Validated across multiple applications.
• Multi-Species — Cross-reactive for translational research. - Host species: Rabbit
- Species reactivity: Human
- Immunogen: E. coli - derived recombinant Human PRDX1 (Lys16-Lys199).
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
- Clonality: Polyclonal
- Isotype: IgG
- Applications: ELISA, IHC, WB
- Target: Thioredoxin-dependent peroxide reductase 2, PAGB, Thioredoxin peroxidase 2, Proliferation-associated gene protein, Thioredoxin-dependent peroxiredoxin 1, PAG, PAGA, Peroxiredoxin-1, Natural killer cell-enhancing factor A, TDPX2, NKEF-A, PRDX1
- Purification: Purified by antigen affinity column.
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
- Background: Peroxiredoxin-1 (PRDX1) is a ~22 kDa protein. Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation.
References:
1. Kang, SW. et al. (1998) The Journal of biological chemistry 273, 6297-302. PMID: 9497357 - Note: For research use only.
Images
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Western blotWestern blot analysis was performed using anti-PRDX1 polyclonal antibody at 1μg/ml on various samples.
Lane 1: HepG2 cell lysate
Lane 2: A549 cell lysate
Lane 3: MCF7 cell lysate
Lane 4: Jurkat cell lysate
Lane 5: Mouse kidney lysate
Datasheet
