Anti-Human G6PD Polyclonal Antibody
- Catalog number: PA11983
- Availability: In Stock
$168.00
- Ex Tax: $168.00
- Description: Anti-Human G6PD Polyclonal Antibody (PA11983) is a rabbit polyclonal antibody detecting G6PD in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights:
• Affinity Purified — Minimal background and high purity for reliable results.
• Multi-Application — Validated across multiple applications.
• Multi-Species — Cross-reactive for translational research. - Host species: Rabbit
- Species reactivity: Human
- Immunogen: E. coli - derived recombinant Human G6PD (Met1-Leu515).
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
- Clonality: Polyclonal
- Isotype: IgG
- Applications: ELISA, IHC, WB
- Target: Glucose-6-phosphate 1-dehydrogenase, G6PD
- Purification: Purified by antigen affinity column.
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
- Background: Glucose-6-phosphate 1-dehydrogenase (G6PD) is a ~59 kDa protein. Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis. Also catalyzes the conversion of NAADPH, which is produced by enzymes such as DUOX1, DUOX2 and NOX5 from NAADP and promotes Ca(2+) signaling during T cell activation, back to NAADP.
References:
1. Gu, F. et al. (2021) Science signaling 14, eabe3800. PMID: 34784249 - Note: For research use only.
Images
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Western blotWestern blot analysis was performed using anti-G6PD polyclonal antibody at 1ug/mL on various samples.
Lane 1: Hela cell lysate
Lane 2: LO2 cell lysate
Lane 3: A431 cell lysate
Lane 4: A549 cell lysate
Datasheet
