Anti-Human EHD1 Polyclonal Antibody
- Catalog number: PA12156
- Availability: In Stock
$168.00
- Ex Tax: $168.00
- Host species: Rabbit
- Species reactivity: Human
- Immunogen: E. coli - derived recombinant Human EHD1 (Thr20-Ser402).
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
- Clonality: Polyclonal
- Isotype: IgG
- Applications: ELISA, IHC, WB
- Target: PAST, EHD1, PAST1, PAST homolog 1, EH domain-containing protein 1, Testilin, hPAST1
- Purification: Purified by antigen affinity column.
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
- Background: EH domain-containing protein 1 (EHD1) is a ~60 kDa protein. ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes vesiculation of endocytic membranes. Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth. Plays a role in myoblast fusion.
References:
1. Cai, B. et al. (2013) The Journal of biological chemistry 288, 30172-30180. PMID: 24019528
2. Naslavsky, N. et al. (2004) Molecular biology of the cell 15, 2410-22. PMID: 15020713
3. George, M. et al. (2007) BMC cell biology 8, 3. PMID: 17233914
4. Rahajeng, J. et al. (2010) The Journal of biological chemistry 285, 31918-22. PMID: 20801876
5. Xie, S. et al. (2019) Journal of cell science 132. PMID: 31615969
6. Lu, Q. et al. (2015) Nature cell biology 17, 228-240. PMID: 25686250 - Note: For research use only.
Images
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Western blotWestern blot analysis was performed using anti-EHD1 polyclonal antibody at 1μg/ml on various samples.
Lane 1: Mouse lung lysate
Lane 2: Rat lung lysate
Datasheet
