Anti-Human PD-1 Reference Antibody (Gilvetmab, RUO)
Anti-Human PD-1 Reference Antibody (Gilvetmab, RUO)  Anti-Human PD-1 Reference Antibody (Gilvetmab, RUO) 

Anti-Human PD-1 Reference Antibody (Gilvetmab, RUO)

  • Catalog number: BS11378
  • Availability: In Stock
  • $176.00

  • Ex Tax: $176.00


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Description: Gilvetmab (BS11378) is a research-grade recombinant antibody targeting CD279. Produced in mammalian cells with native-like glycosylation.
Highlights:
• Research Grade — For PK/PD studies, assay development, and ADA research.
• Native Glycosylation — Mammalian expression ensures native-like patterns.
Host species: Caninized
Isotype: IgG2-kappa
Species reactivity: Dog
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 1.04mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: CD279/PDCD1/PD1
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: AH-PD1,CAS:1808081-43-7
Background: Gilvetmab is a potent caninized anti-PD-1 monoclonal antibody. gilvetmab blocks the interaction between PD-1 and its ligand PDL-1.
References:
1. Diagnostic value of soluble programmed cell death protein-1 in type-1 autoimmune hepatitis in Egyptian children., PMID:31762332
Note: For research use only. Not suitable for clinical or therapeutic use.

Images

  • Bioactivity for Anti-Human PD-1 Reference Antibody (Gilvetmab, RUO)
    Bioactivity

    Detects Dog CD279 in indirect ELISAs.

  • Western blot for Anti-Human PD-1 Reference Antibody (Gilvetmab, RUO)
    Western blot

    Western blot analysis was performed using anti-dog PD1 monoclonal antibody at 1ug/mL on various samples.
    Lane 1: recombinant Dog CD279/PDCD1/PD1 (Catalog No: PV10041)
    Lane 2: negative control

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