Anti-Human LMNB2 Polyclonal Antibody

Size

50 µg

100 µg (+$110.00)

Qty

Host species: Rabbit
Species reactivity: Human
Immunogen: E. coli - derived recombinant Human LMNB2 (Gly461-Ser581).
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Clonality: Polyclonal
Isotype: IgG
Applications: ELISA, IHC, WB
Target: LMN2, LMNB2, Lamin-B2
Purification: Purified by antigen affinity column.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background: Lamin-B2 (LMNB2) is a ~69 kDa protein. Lamins are intermediate filament proteins that assemble into a filamentous meshwork, and which constitute the major components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane. Lamins provide a framework for the nuclear envelope, bridging the nuclear envelope and chromatin, thereby playing an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. The structural integrity of the lamina is strictly controlled by the cell cycle, as seen by the disintegration and formation of the nuclear envelope in prophase and telophase, respectively.
References:
1. Parry, DA. et al. (2021) Genetics in medicine : official journal of the American College of Medical Genetics 23, 408-414. PMID: 33033404
Note: For research use only.

Datasheet

$168.00