Anti-Human B4GALT6 Polyclonal Antibody
- Catalog number: PA13697
- Availability: In Stock
$168.00
- Ex Tax: $168.00
- Host species: Rabbit
- Species reactivity: Human
- Immunogen: E. coli - derived recombinant Human B4GALT6 (Glu125-Tyr382).
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
- Clonality: Polyclonal
- Isotype: IgG
- Applications: ELISA, IHC, WB
- Target: b4Gal-T6, Beta4Gal-T6, UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 6, Beta-1,4-galactosyltransferase 6, Lactosylceramide synthase, UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase, Beta-1,4-GalTase 6, Glucosylceramide beta-1,4-galactosyltransferase, LacCer synthase, UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 6, B4GALT6
- Purification: Purified by antigen affinity column.
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
- Background: Beta-1,4-galactosyltransferase 6 (B4GALT6) is a ~44 kDa protein. Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation.
References:
1. Chatterjee, S. et al. (1992) The Journal of biological chemistry 267, 7148-53. PMID: 155192
2. Yamaji, T. et al. (2014) PloS one 9, e88124. PMID: 2449843
3. Chatterjee, S. et al. (1987) Biochimica et biophysica acta 923, 136-42. PMID: 3099851 - Note: For research use only.
Images
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Western blotWestern blot analysis was performed using anti-B4GALT6 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse heart lysate
Lane 2: Rat heart lysate
