Anti-Mouse CD147/BSG Polyclonal Antibody

Size

50 µg

100 µg (+$110.00)

Qty

Host species: Rabbit
Species reactivity: Mouse
Immunogen: E. coli - derived recombinant Mouse CD147/BSG (Ala22-Arg325).
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Clonality: Polyclonal
Isotype: IgG
Applications: ELISA, IHC, WB
Target: Basigin (Basic immunoglobulin superfamily) (HT7 antigen) (Membrane glycoprotein gp42) (CD antigen CD147)
Purification: Purified by antigen affinity column.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background: Basigin (CD147/BSG) is a ~42 kDa protein. Essential for normal retinal maturation and development. Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors. In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors.
References:
1. Hori, K. et al. (2000) Investigative ophthalmology & visual science 41, 3128-33. PMID: 10967074
2. Ochrietor, JD. et al. (2001) Experimental eye research 72, 467-77. PMID: 11273674
3. Ochrietor, JD. et al. (2002) Vision research 42, 447-53. PMID: 1185376
4. Aït-Ali, N. et al. (2015) Cell 161, 817-32. PMID: 25957687
Note: For research use only.

Datasheet

$168.00