Anti-Human ADAMTSL5/THSD6 & ALB Bispecific Reference Antibody (Isecarosmab, RUO)

Description: Isecarosmab (BS11458) is a research-grade recombinant antibody targeting A disintegrin and metalloproteinase with thrombospondin m.... Produced in mammalian cells with native-like glycosylation.
Highlights:
• Research Grade — For PK/PD studies, assay development, and ADA research.
• Native Glycosylation — Mammalian expression ensures native-like patterns.
Host species: Humanized(Lama/glama)
Isotype: VH-VH'
Species reactivity: Human
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 1mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: Thrombospondintype-1domain-containingprotein6,ADAMTSL5,ADAMTS-likeprotein5,THSD6,ADAMTSL-5,ALB,Albumin
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: Bispecific,M-6495,CAS:2254082-79-4
Background: Isecarosmab (M-6495) is an anti-ADAMTS monoclonal antibody (mAb) with a KD value of 3.65 pM. Isecarosmab has chondroprotective and anti-inflammatory activities. Isecarosmab can bind albumin to extend plasma half-life.
Note: For research use only. Not suitable for clinical or therapeutic use.