Anti-Human CD23 Reference Antibody (Lumiliximab, RUO)
- Catalog number: BS10104
- Availability: In Stock
$176.00
- Ex Tax: $176.00
Description: Lumiliximab (BS10104) is a research-grade recombinant antibody targeting CD23A. Produced in mammalian cells with native-like glycosylation.
Highlights:
• Research Grade — For PK/PD studies, assay development, and ADA research.
• Native Glycosylation — Mammalian expression ensures native-like patterns.
Host species: Chimeric
Isotype: IgG1-kappa
Species reactivity: Human
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 1.66mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: LymphocyteIgEreceptor,C-typelectindomainfamily4memberJ,LowaffinityimmunoglobulinepsilonFcreceptor,CD23A,BLAST-2,ImmunoglobulinE-bindingfactor,IGEBF,CD23,Fc-epsilon-RII,CLEC4J,FCE2,FCER2
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: IDEC-152,P5E8,CAS:357613-86-6
Background: Low affinity immunoglobulin epsilon Fc receptor (CD23/FCER2) is a ~36 kDa protein. Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway.
References:
1. Pirron, U. et al. (1990) European journal of immunology 20, 1547-51. PMID: 2167225
2. Vouldoukis, I. et al. (1995) Proceedings of the National Academy of Sciences of the United States of America 92, 7804-8. PMID: 7544003
Note: For research use only. Not suitable for clinical or therapeutic use.
Highlights:
• Research Grade — For PK/PD studies, assay development, and ADA research.
• Native Glycosylation — Mammalian expression ensures native-like patterns.
Host species: Chimeric
Isotype: IgG1-kappa
Species reactivity: Human
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 1.66mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: LymphocyteIgEreceptor,C-typelectindomainfamily4memberJ,LowaffinityimmunoglobulinepsilonFcreceptor,CD23A,BLAST-2,ImmunoglobulinE-bindingfactor,IGEBF,CD23,Fc-epsilon-RII,CLEC4J,FCE2,FCER2
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: IDEC-152,P5E8,CAS:357613-86-6
Background: Low affinity immunoglobulin epsilon Fc receptor (CD23/FCER2) is a ~36 kDa protein. Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway.
References:
1. Pirron, U. et al. (1990) European journal of immunology 20, 1547-51. PMID: 2167225
2. Vouldoukis, I. et al. (1995) Proceedings of the National Academy of Sciences of the United States of America 92, 7804-8. PMID: 7544003
Note: For research use only. Not suitable for clinical or therapeutic use.
Images
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SDS-PAGESDS-PAGE for Research Grade Lumiliximab.
