Anti-Human IDH3B Polyclonal Antibody

Anti-Human IDH3B Polyclonal Antibody

  • Catalog number: PA14619
  • Availability: In Stock
  • $168.00

  • Ex Tax: $168.00


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  • Description: Anti-Human IDH3B Polyclonal Antibody (PA14619) is a rabbit polyclonal antibody detecting IDH3B in ELISA, IHC, WB. Suitable for Human.
    Highlights:
    • Affinity Purified — Minimal background and high purity for reliable results.
    • Multi-Application — Validated across multiple applications.
  • Host species: Rabbit
  • Species reactivity: Human
  • Immunogen: E. coli - derived recombinant Human IDH3B (Ser48-Ser385).
  • Form: Liquid
  • Storage buffer: 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
  • Clonality: Polyclonal
  • Isotype: IgG
  • Applications: ELISA, IHC, WB
  • Target: Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial, Isocitric dehydrogenase subunit beta, NAD(+)-specific ICDH subunit beta, IDH3B
  • Purification: Purified by antigen affinity column.
  • Stability and Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
  • Background: Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (IDH3B) is a ~42 kDa protein. Plays a structural role to facilitate the assembly and ensure the full activity of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
  • Note: For research use only.

Images

  • Western blot for Anti-Human IDH3B Polyclonal Antibody
    Western blot

    Western blot analysis was performed using anti-IDH3B polyclonal antibody at 1ug/mL on various samples.
    Lane 1: Mouse brain lysate
    Lane 2: Mouse heart lysate
    Lane 3: Rat heart lysate

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