Anti-Human USP4 Polyclonal Antibody
- Catalog number: PA14855
- Availability: In Stock
$168.00
- Ex Tax: $168.00
- Description: Anti-Human USP4 Polyclonal Antibody (PA14855) is a rabbit polyclonal antibody detecting USP4 in ELISA, IHC, WB. Suitable for Human, Bovine, Rat, and Mouse.
Highlights:
• Affinity Purified — Minimal background and high purity for reliable results.
• Multi-Application — Validated across multiple applications.
• Multi-Species — Cross-reactive for translational research. - Host species: Rabbit
- Species reactivity: Human
- Immunogen: E. coli - derived recombinant Human USP4 (Asp12-Glu220).
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
- Clonality: Polyclonal
- Isotype: IgG
- Applications: ELISA, IHC, WB
- Target: Ubiquitin carboxyl-terminal hydrolase 4, 3.4.19.12, Deubiquitinating enzyme 4, Ubiquitin thioesterase 4, Ubiquitin-specific-processing protease 4, Ubiquitous nuclear protein homolog, USP4, UNP, UNPH
- Purification: Purified by antigen affinity column.
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
- Background: Ubiquitin carboxyl-terminal hydrolase 4 (USP4) is a ~108 kDa protein. Deubiquitinating enzyme that removes conjugated ubiquitin from target proteins. Deubiquitinates PDPK1. Deubiquitinates TRIM21. Deubiquitinates receptor ADORA2A which increases the amount of functional receptor at the cell surface. Deubiquitinates HAS2.
References:
1. Wada, K. et al. (2006) Biochemical and biophysical research communications 339, 731-6. PMID: 16316627
2. Milojevic, T. et al. (2006) Molecular pharmacology 69, 1083-94. PMID: 16339847
3. Wada, K. et al. (2006) Biochemical and biophysical research communications 342, 253-8. PMID: 16472766
4. Song, EJ. et al. (2010) Genes & development 24, 1434-47. PMID: 20595234
5. Uras, IZ. et al. (2012) PloS one 7, e31003. PMID: 2234742
6. Clerici, M. et al. (2014) Nature communications 5, 5399. PMID: 25404403
7. Mehić, M. et al. (2017) Oncogenesis 6, e348. PMID: 28604766
8. Deng, L. et al. (2019) Cell research 29, 136-150. PMID: 30514904
9. Chu, F. et al. (2024) Proceedings of the National Academy of Sciences of the United States of America 121, e2401174121. PMID: 39589880 - Note: For research use only.
Images
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Western blotWestern blot analysis was performed using anti-USP4 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Hela cell lysate
Lane 2: Jurkat cell lysate
Datasheet
