Anti-Mouse ADA/Adenosine deaminase Polyclonal Antibody
- Catalog number: PA14994
- Availability: In Stock
$168.00
- Ex Tax: $168.00
- Description: Anti-Mouse ADA/Adenosine deaminase Polyclonal Antibody (PA14994) is a rabbit polyclonal antibody detecting Adenosine deaminase in ELISA, IHC, WB. Suitable for Mouse.
Highlights:
• Affinity Purified — Minimal background and high purity for reliable results.
• Multi-Application — Validated across multiple applications. - Host species: Rabbit
- Species reactivity: Mouse
- Immunogen: E. coli - derived recombinant Mouse ADA/Adenosine deaminase (Met1-Gln352).
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
- Clonality: Polyclonal
- Isotype: IgG
- Applications: ELISA, IHC, WB
- Target: Adenosine deaminase, 3.5.4.4, Adenosine aminohydrolase, Ada
- Purification: Purified by antigen affinity column.
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
- Background: Adenosine deaminase (ADA) is a ~39 kDa protein. Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion.
References:
1. Xu, PA. et al. (2000) Biochemical and biophysical research communications 269, 749-57. PMID: 10720488
2. Mohamedali, KA. et al. (1996) Biochemistry 35, 1672-80. PMID: 8634299
3. Sideraki, V. et al. (1996) Biochemistry 35, 7862-72. PMID: 8672487
4. Sideraki, V. et al. (1996) Biochemistry 35, 15019-28. PMID: 8942668
5. Blackburn, MR. et al. (1997) Development (Cambridge, England) 124, 3089-97. PMID: 927295
6. Apasov, SG. et al. (2001) The Journal of clinical investigation 108, 131-41. PMID: 11435465
7. Li, G. et al. (2015) Pharmacology research & perspectives 3, e00121. PMID: 26038697 - Note: For research use only.
Images
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Western blotWestern blot analysis was performed using anti-ADA polyclonal antibody at ADA on various samples.
Lane 1: Jurkat cell lysate
Lane 2: MOLT-4 cell lysate
Lane 3: Mouse thymus lysate
Lane 4: Mouse stomach lysate
Lane 5: Rat spleen lysate
