Anti-Ramucirumab Polyclonal Antibody
- Catalog number: PA15347
- Availability: In Stock
$352.00
- Ex Tax: $352.00
- Host species: Rabbit
- Specificity: The product is specific for Ramucirumab. This antibody serves as an excellent positive control for Ramucirumab immunogenicity (ADA) assays.
- Immunogen: Ramucirumab
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
- Clonality: Polyclonal
- Isotype: IgG
- Applications: ELISA
- Purification: Antigen affinity purification.
- Stability and Storage: The product can be stored for 2-3 weeks at 2-8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.
- Background: Ramucirumab (LY3009806) is a human monoclonal antibody (IgG1) against vascular endothelial growth factor receptor 2 (VEGFR2), a type II trans-membrane tyrosine kinase receptor expressed on endothelial cells. By binding to VEGFR2, ramucirumab prevents binding of its ligands (VEGF-A, VEGF-C, and VEGF-D), thereby preventing VEGF-stimulated receptor phosphorylation and downstream ligand-induced proliferation, permeability, and migration of human endothelial cells.
- Alternative Names: Rabbit polyclonal to REGN-10987.
- Note: Antibodysystem can customize this product per customer's request including product size, buffer components, etc. For research use only.
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