Anti-Human NT-ProBNP Monoclonal Antibody (1A345)
- Catalog number: MA10341
- Availability: In Stock
$194.00
- Ex Tax: $194.00
Description: Anti-Human NT-ProBNP Monoclonal Antibody (1A345) [1A345] (MA10341) is a mouse monoclonal antibody detecting NT-proBNP in CLIA. Suitable for Human.
Host species: Mouse
Conjugation: None
Species reactivity: Human
Isotype: IgG
Immunogen: Human NT-ProBNP Protein.
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Clonality: Monoclonal
Applications: CLIA
Target: Natriuretic peptides B, Brain natriuretic factor prohormone, preproBNP, proBNP, Gamma-brain natriuretic peptide, Iso-ANP, NT-proBNP, NT-pro-BNP, NT-proBNP(1-76), proBNP(3-108), NPPB
Purification: Protein A/G purified from cell culture supernatant.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: N/A
Background: Natriuretic peptides B (NT-ProBNP) is a ~14 kDa protein. Cardiac hormone that plays a key role in mediating cardio-renal homeostasis. May also function as a paracrine antifibrotic factor in the heart. Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses. Involved in regulating the extracellular fluid volume and maintaining the fluid-electrolyte balance through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Binds the clearance receptor NPR3.
References:
1. Koller, KJ. et al. (1991) Science (New York, N.Y.) 252, 120-3. PMID: 1672777
2. Heublein, DM. et al. (2007) Hypertension (Dallas, Tex. : 1979) 49, 1114-9. PMID: 1737204
3. Yoshimura, M. et al. (1991) Circulation 84, 1581-8. PMID: 1914098
4. Jensen, KT. et al. (1998) The American journal of physiology 274, F63-72. PMID: 9458824
5. Liang, F. et al. (2007) Journal of the American College of Cardiology 49, 1071-8. PMID: 17349887
6. Ralat, LA. et al. (2011) The Journal of biological chemistry 286, 4670-9. PMID: 21098034
7. Huntley, BK. et al. (2015) Circulation. Heart failure 8, 89-97. PMID: 25339504
Note: For research use only.
Host species: Mouse
Conjugation: None
Species reactivity: Human
Isotype: IgG
Immunogen: Human NT-ProBNP Protein.
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Clonality: Monoclonal
Applications: CLIA
Target: Natriuretic peptides B, Brain natriuretic factor prohormone, preproBNP, proBNP, Gamma-brain natriuretic peptide, Iso-ANP, NT-proBNP, NT-pro-BNP, NT-proBNP(1-76), proBNP(3-108), NPPB
Purification: Protein A/G purified from cell culture supernatant.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: N/A
Background: Natriuretic peptides B (NT-ProBNP) is a ~14 kDa protein. Cardiac hormone that plays a key role in mediating cardio-renal homeostasis. May also function as a paracrine antifibrotic factor in the heart. Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses. Involved in regulating the extracellular fluid volume and maintaining the fluid-electrolyte balance through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Binds the clearance receptor NPR3.
References:
1. Koller, KJ. et al. (1991) Science (New York, N.Y.) 252, 120-3. PMID: 1672777
2. Heublein, DM. et al. (2007) Hypertension (Dallas, Tex. : 1979) 49, 1114-9. PMID: 1737204
3. Yoshimura, M. et al. (1991) Circulation 84, 1581-8. PMID: 1914098
4. Jensen, KT. et al. (1998) The American journal of physiology 274, F63-72. PMID: 9458824
5. Liang, F. et al. (2007) Journal of the American College of Cardiology 49, 1071-8. PMID: 17349887
6. Ralat, LA. et al. (2011) The Journal of biological chemistry 286, 4670-9. PMID: 21098034
7. Huntley, BK. et al. (2015) Circulation. Heart failure 8, 89-97. PMID: 25339504
Note: For research use only.
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SDS-PAGESDS-PAGE for Anti-Human HCG Monoclonal Antibody (1A372)
