Anti-Mouse ZNF423 Antibody (N328B/37R)

Description: Anti-Mouse ZNF423 Antibody (N328B/37R) [N328B/37R] (RA10535) is a mouse monoclonal antibody detecting ZNF423 in ICC, IHC, WB. Suitable for Human and Mouse.
Highlights:
• Multi-Application — Validated across multiple applications.
Host species: Mouse
Isotype: IgG1, kappa
Species reactivity: Human, Mouse
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1.13 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ICC, IHC, WB
Target: Zinc finger protein 423, KIAA0760, Olf1/EBF-associated zinc finger protein, Smad- and Olf-interacting zinc finger protein, NPHP14, OAZ, hOAZ, ZNF423
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Zinc finger protein 423 (ZNF423) is a ~145 kDa protein. Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation; this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons.
Note: For research use only.