Anti-Parainfluenza virus 5/PIV5 Protein P Antibody (SAA0288)

Description: Anti-Parainfluenza virus 5/PIV5 Protein P Antibody (SAA0288) [SAA0288] (RA10607) is a mouse monoclonal antibody detecting Protein P in ELISA, Neutralization.
Host species: Mouse
Isotype: IgG2a, kappa
Species reactivity: Parainfluenza virus 5 (PIV5)
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 4.13 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA, Neutralization
Target: Phosphoprotein, Protein P, P/V
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Phosphoprotein (Protein P) is a ~42 kDa protein. Essential cofactor of the RNA polymerase L that plays a central role in the transcription and replication by forming the polymerase complex with RNA polymerase L and recruiting L to the genomic N-RNA template for RNA synthesis. Also plays a central role in the encapsidation of nascent RNA chains by forming the encapsidation complex with the nucleocapsid protein N (N-P complex). Acts as a chaperone for newly synthesized free N protein, so-called N0, allowing encapsidation of nascent RNA chains during replication. The nucleoprotein protein N prevents excessive phosphorylation of P, which leads to down-regulation of viral transcription/ replication. Participates, together with N, in the formation of viral factories (viroplasms), which are large inclusions in the host cytoplasm where replication takes place.
Note: For research use only.