Anti-Human papillomavirus type 16 E7/Protein E7 Nanobody (SAA1326)

Description: Anti-Human papillomavirus type 16 E7/Protein E7 Nanobody (SAA1326) [SAA1326] (RA11693) is a alpaca monoclonal antibody detecting Protein E7 in ELISA.
Host species: Alpaca
Isotype: VHH-8His-Cys-tag
Species reactivity: Human papillomavirus type 16
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA
Target: Protein E7, E7
Purification: Purified by Nickel column.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Protein E7 (ProteinE7) is a ~11 kDa protein. Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.
Note: For research use only.