Anti-Clostridium tetani tetX/Tetanus toxin Nanobody (SAA1236)

Description: Anti-Clostridium tetani tetX/Tetanus toxin Nanobody (SAA1236) [SAA1236] (RA11739) is a alpaca monoclonal antibody detecting Tetanus toxin in ELISA, FCM, SPR.
Highlights:
• Multi-Application — Validated across multiple applications.
• Flow Cytometry — Validated for flow cytometry applications.
Host species: Alpaca
Isotype: VHH-8His-Cys-tag
Species reactivity: Clostridium tetani (strain Massachusetts / E88)
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA, FCM, SPR
Target: Tetanus toxin, 3.4.24.68, Tentoxylysin, Tetanus toxin light chain, Tetanus toxin chain L, Tetanus toxin heavy chain, Tetanus toxin chain H, tetX, CTC_p60
Purification: Purified by Nickel column.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Tetanus toxin (tetX) is a ~150 kDa protein. Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrevin-2.
Note: For research use only.