Anti-HIV-1 nef/F-protein protein Nanobody (SAA1423)

Description: Anti-HIV-1 nef/F-protein protein Nanobody (SAA1423) [SAA1423] (RA11825) is a alpaca monoclonal antibody detecting Protein Nef in BIF, ELISA, IF.
Highlights:
• Multi-Application — Validated across multiple applications.
Host species: Alpaca
Isotype: VHH-8His-Cys-tag
Species reactivity: Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2) (HIV-1)
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: BIF, ELISA, IF
Target: Protein Nef, 3'ORF, Negative factor, F-protein, C-terminal core protein, nef
Purification: Purified by Nickel column.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Protein Nef (F-protein/Negative factor) is a ~24 kDa protein. Factor of infectivity and pathogenicity, required for optimal virus replication. Alters numerous pathways of T-lymphocyte function and down-regulates immunity surface molecules in order to evade host defense and increase viral infectivity. Alters the functionality of other immunity cells, like dendritic cells, monocytes/macrophages and NK cells.
Note: For research use only.