InVivoMAb Anti-Staphylococcus aureus entB/SEB Antibody (Iv0156)

Description: InVivoMAb Anti-Staphylococcus aureus entB/SEB Antibody (Iv0156) [Iv0156] (RA11850) is a mouse monoclonal antibody detecting Enterotoxin type B in ELISA, Neutralization.
Host species: Mouse
Isotype: IgG2a
Species reactivity: Staphylococcus aureus
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA, Neutralization
Target: Enterotoxin type B, SEB, entB
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Enterotoxin type B (entB/SEB) is a ~31 kDa protein. Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex activates a large number of T-lymphocytes initiating a systemic release of pro-inflammatory cytokines. Also causes the intoxication staphylococcal food poisoning syndrome.
References:
1. Marrack, P. et al. (1990) The Journal of experimental medicine 171, 455-64. PMID: 230378
2. Rödström, KE. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 193, 1998-2004. PMID: 25015819
Note: For research use only. Not suitable for clinical or therapeutic use.