InVivoMAb Anti-Influenza A virus Neuraminidase/NA Antibody (1E01#)

Description: InVivoMAb Anti-Influenza A virus Neuraminidase/NA Antibody (1E01#) [1E01#] (RA11904) is a human monoclonal antibody detecting Neuraminidase in ELISA, Neutralization.
Host species: Human
Isotype: IgG1
Species reactivity: Influenza A virus (strain A/Japan/305/1957 H2N2) (Q1K9Q1), Influenza A virus (strain A/RI/5-/1957 H2N2) (P03484)
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA, Neutralization
Target: Neuraminidase, 3.2.1.18, NA
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Neuraminidase (NA) is a ~51 kDa protein. Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates. Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release. Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface. These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell. Otherwise, infection would be limited to one round of replication.
Note: For research use only. Not suitable for clinical or therapeutic use.