InVivoMAb Anti-HRSV G/Major surface glycoprotein G Antibody (CB017.5)

Description: InVivoMAb Anti-HRSV G/Major surface glycoprotein G Antibody (CB017.5) [CB017.5] (RA11931) is a human monoclonal antibody detecting Major surface glycoprotein G in ELISA, Neutralization, WB.
Highlights:
• Multi-Application — Validated across multiple applications.
Host species: Human
Isotype: IgG1, lambda
Species reactivity: Human respiratory syncytial virus A (strain rsb6256)
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA, Neutralization, WB
Target: Major surface glycoprotein G, Attachment glycoprotein G, Membrane-bound glycoprotein, mG, Mature secreted glycoprotein G, Mature sG, G
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Major surface glycoprotein G is a ~32 kDa protein. Attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, lacks both neuraminidase and hemagglutinating activities.
Note: For research use only. Not suitable for clinical or therapeutic use.