Anti-Mouse MPO/Myeloperoxidase Antibody (6D6)

Description: Anti-Mouse MPO/Myeloperoxidase Antibody (6D6) [6D6] (RA11956) is a mouse monoclonal antibody detecting Myeloperoxidase in ELISA, IF, SPR, WB. Suitable for Mouse.
Highlights:
• Multi-Application — Validated across multiple applications.
Host species: Mouse
Isotype: IgG2a
Species reactivity: Mouse
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA, IF, SPR, WB
Target: Mpo, Myeloperoxidase, Myeloperoxidase light chain, Myeloperoxidase heavy chain
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Myeloperoxidase (MPO) is a ~81 kDa protein. Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low density lipoprotein particles and limits vascular damage.
References:
1. Gaut, JP. et al. (2001) Proceedings of the National Academy of Sciences of the United States of America 98, 11961-6. PMID: 11593004
Note: For research use only.