Anti-Vaccinia A33R Antibody (A27D7)

Description: Anti-Vaccinia A33R Antibody (A27D7) [A27D7] (RA11996) is a human monoclonal antibody detecting A33R in ELISA, Neutralization, WB, IHC, IF. Suitable for Vaccinia.
Highlights:
• Multi-Application — Validated across multiple applications.
Host species: Human
Isotype: IgG1, kappa
Species reactivity: Vaccinia
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 2.42 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA, Neutralization
Target: Protein A33, VACWR156, A33R
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Protein OPG161 (A33R) is a ~20 kDa protein. Forms a complex with OPG162 and OPG190 to coordinate the incorporation of OPG164 into wrapped enveloped virion (EV) membranes and, subsequently, the production of actin tails. Therefore plays an essential role in efficient cell-to-cell spread of viral particles.
References:
1. Wolffe, EJ. et al. (2001) Journal of virology 75, 303-10. PMID: 1111960
2. Breiman, A. et al. (2013) The Journal of general virology 94, 720-725. PMID: 23255618
3. Monticelli, SR. et al. (2020) Journal of virology 94. PMID: 31941777
Note: For research use only.