Anti-Human FSHB Antibody (SAA1474)

Description: Anti-Human FSHB Antibody (SAA1474) [SAA1474] (RA12053) is a mouse monoclonal antibody detecting FSHB in Blocking, ELISA. Suitable for Human.
Host species: Mouse
Isotype: IgG2a, kappa
Species reactivity: Human
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Blocking, ELISA
Target: Follicle-stimulating hormone beta subunit, Follitropin beta chain, FSH-beta, FSH-B, FSHB, Follitropin subunit beta
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Follitropin subunit beta (FSHB) is a ~14 kDa protein. Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs.
References:
1. Jiang, X. et al. (2014) The Journal of biological chemistry 289, 14273-82. PMID: 24692546
2. Keene, JL. et al. (1989) The Journal of biological chemistry 264, 4769-75. PMID: 2494176
3. Maroulis, GB. et al. (1977) Fertility and sterility 28, 818-22. PMID: 407105
4. Matthews, CH. et al. (1993) Nature genetics 5, 83-6. PMID: 8220432
Note: For research use only.