InVivoMAb Anti-Human MUC5AC Antibody (Iv0182)

Description: InVivoMAb Anti-Human MUC5AC Antibody (Iv0182) [Iv0182] (RA12058) is a human monoclonal antibody detecting Mucin-5 subtype AC in ELISA, IHC, Neutralization. Suitable for Human.
Highlights:
• Multi-Application — Validated across multiple applications.
Host species: Human
Isotype: IgG1, kappa
Species reactivity: Human
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA, IHC, Neutralization
Target: Mucin-5 subtype AC, tracheobronchial, Gastric mucin, Mucin-5AC, TBM, MUC-5AC, Tracheobronchial mucin, Major airway glycoprotein, MUC5AC, MUC5
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Mucin-5AC (MUC5AC) is a ~585 kDa protein. Gel-forming glycoprotein of gastric and respiratory tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microorganisms and particles that are subsequently removed by the mucociliary system. Interacts with H.pylori in the gastric epithelium, Barrett's esophagus as well as in gastric metaplasia of the duodenum (GMD).
References:
1. Van de Bovenkamp, JH. et al. (2003) Helicobacter 8, 521-32. PMID: 14535999
2. Perez-Vilar, J. et al. (2004) Glycobiology 14, 325-37. PMID: 14718370
Note: For research use only. Not suitable for clinical or therapeutic use.