InVivoMAb Anti-Human β-tryptase/TPSAB1 Antibody (31A)

Description: InVivoMAb Anti-Human β-tryptase/TPSAB1 Antibody (31A) [31A] (RA12065) is a mouse monoclonal antibody detecting TPSB1 in Blocking, ELISA. Suitable for Human.
Host species: Mouse
Isotype: IgG2a, kappa
Species reactivity: Human
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Blocking, ELISA
Target: TPSB1, TPS2, Tryptase I, Tryptase-1, TPSAB1, Tryptase alpha-1, Tryptase alpha/beta-1, TPS1
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Tryptase alpha/beta-1 (TPSAB1/Tryptase-1) is a ~30 kDa protein. Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates.
References:
1. Jackson, NE. et al. (2008) The Journal of biological chemistry 283, 34178-87. PMID: 18854315
Note: For research use only. Not suitable for clinical or therapeutic use.