InVivoMAb Anti-REBOV/SEBOV/TAFV/ZEBOV NP/Nucleoprotein Antibody (MJ20)

Description: InVivoMAb Anti-REBOV/SEBOV/TAFV/ZEBOV NP/Nucleoprotein Antibody (MJ20) [MJ20] (RA12118) is a human monoclonal antibody detecting Nucleoprotein in ELISA, IF, Neutralization, SPR.
Highlights:
• Multi-Application — Validated across multiple applications.
Host species: Human
Isotype: IgG
Species reactivity: Reston ebolavirus (strain Reston-89) (REBOV) (Reston Ebola virus), Zaire ebolavirus (strain Mayinga-76) (ZEBOV) (Zaire Ebola virus), Bundibugyo ebolavirus, Tai Forest ebolavirus
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA, IF, Neutralization, SPR
Target: Nucleoprotein, Ebola NP, eNP, Nucleocapsid protein, Protein N, NP
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Nucleoprotein (NP) is a ~83 kDa protein. Oligomerizes into helical capsid to encapsidate the viral genome, protecting it from nucleases and the cellular innate immune response. VP35 binds to and stabilizes monomeric NP, keeping it soluble. Upon virus replication, NP is recruited to bind cooperatively viral genomic RNA and VP35 is released. The encapsidated genomic RNA is termed the nucleocapsid and serves as template for transcription and replication. The nucleocapsid is helical with a pitch of 10.81 NP per turn and a diameter of about 22nm.
Note: For research use only. Not suitable for clinical or therapeutic use.