Anti-Human FSTL1 Antibody (SAA1665)

Description: Anti-Human FSTL1 Antibody (SAA1665) [SAA1665] (RA12309) is a mouse monoclonal antibody detecting FSTL1 in ELISA. Suitable for Human.
Host species: Mouse
Isotype: IgG2a, kappa
Species reactivity: Human
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA
Target: FSTL1, Follistatin-related protein 1, Follistatin-like protein 1, FRP
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Follistatin-related protein 1 (FSTL1) is a ~34 kDa protein. Secreted glycoprotein that is involved in various physiological processes, such as angiogenesis, regulation of the immune response, cell proliferation and differentiation. Plays a role in the development of the central nervous system, skeletal system, lungs, and ureter. Promotes endothelial cell survival, migration and differentiation into network structures in an AKT-dependent manner. Also promotes survival of cardiac myocytes. Initiates various signaling cascades by activating different receptors on the cell surface such as DIP2A, TLR4 or BMP receptors.
References:
1. Murakami, K. et al. (2012) FEBS letters 586, 319-24. PMID: 22265692
2. Jin, X. et al. (2017) Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 44, 1616-1628. PMID: 29212066
3. Ouchi, N. et al. (2010) The Journal of biological chemistry 285, 7127-34. PMID: 20054002
Note: For research use only.