Anti-Human CDK5R1 Antibody (SAA1679)

Description: Anti-Human CDK5R1 Antibody (SAA1679) [SAA1679] (RA12323) is a mouse monoclonal antibody detecting CDK5R1 in ELISA. Suitable for Human.
Host species: Mouse
Isotype: IgG2a, kappa
Species reactivity: Human
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA
Target: NCK5A, CDK5R, CDK5R1, Cyclin-dependent kinase 5 activator 1, Cyclin-dependent kinase 5 regulatory subunit 1, CDK5 activator 1, TPKII regulatory subunit, Tau protein kinase II 23 kDa subunit, p23, p35, p25
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Cyclin-dependent kinase 5 activator 1 (CDK5R1) is a ~34 kDa protein. p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-BMAL1 heterodimer in association with altered stability and subcellular distribution.
Note: For research use only.