Anti-Human EPN1 Antibody (SAA1730)

Description: Anti-Human EPN1 Antibody (SAA1730) [SAA1730] (RA12374) is a mouse monoclonal antibody detecting EPN1 in ELISA. Suitable for Human.
Host species: Mouse
Isotype: IgG2a, kappa
Species reactivity: Human
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA
Target: EH domain-binding mitotic phosphoprotein, EPN1, EPS-15-interacting protein 1, Epsin-1
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Epsin-1 (EPN1) is a ~60 kDa protein. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations. Regulates receptor-mediated endocytosis.
References:
1. Nakashima, S. et al. (1999) The EMBO journal 18, 3629-42. PMID: 10393179
2. Morinaka, K. et al. (1999) Oncogene 18, 5915-22. PMID: 10557078
Note: For research use only.