Anti-Human EDA1 Antibody (SAA1763)

Description: Anti-Human EDA1 Antibody (SAA1763) [SAA1763] (RA12407) is a mouse monoclonal antibody detecting EDA in ELISA. Suitable for Human.
Host species: Mouse
Isotype: IgG2a, kappa
Species reactivity: Human
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA
Target: Isoform 1 of Ectodysplasin-A, Ectodermal dysplasia protein, EDA protein, Ectodysplasin-A, membrane form, Ectodysplasin-A, secreted form, EDA, ED1, EDA2
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Ectodysplasin-A (EDA1) is a ~41 kDa protein. Cytokine which is involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Functions as a ligand activating the DEATH-domain containing receptors EDAR and EDA2R. May also play a role in cell adhesion.
References:
1. Yan, M. et al. (2000) Science (New York, N.Y.) 290, 523-7. PMID: 11039935
2. Shen, W. et al. (2016) PloS one 11, e0154884. PMID: 27144394
3. Yu, K. et al. (2021) Molecular genetics & genomic medicine 9, e1824. PMID: 34582123
4. Kere, J. et al. (1996) Nature genetics 13, 409-16. PMID: 8696334
Note: For research use only.