Anti-Human TSPO Antibody (SAA1799)

Description: Anti-Human TSPO Antibody (SAA1799) [SAA1799] (RA12443) is a mouse monoclonal antibody detecting TSPO in ELISA. Suitable for Human.
Host species: Mouse
Isotype: IgG2a, kappa
Species reactivity: Human
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA
Target: PKBS, TSPO, MBR, PBR, BZRP, Translocator protein, Peripheral-type benzodiazepine receptor, Mitochondrial benzodiazepine receptor
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Translocator protein (TSPO) is a ~18 kDa protein. Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides.
References:
1. Taylor, JM. et al. (2014) Clinical science (London, England : 1979) 127, 603-13. PMID: 24814875
2. Riond, J. et al. (1991) European journal of biochemistry 195, 305-11. PMID: 1847678
Note: For research use only.