Anti-Human HARS1 Antibody (SAA1815)

Description: Anti-Human HARS1 Antibody (SAA1815) [SAA1815] (RA12459) is a mouse monoclonal antibody detecting HARS1 in ELISA. Suitable for Human.
Host species: Mouse
Isotype: IgG2a, kappa
Species reactivity: Human
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA
Target: HRS, HARS, HisRS, Histidyl-tRNA synthetase, HARS1, Histidine--tRNA ligase, cytoplasmic
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Histidine--tRNA ligase, cytoplasmic (HARS1) is a ~57 kDa protein. Catalyzes the ATP-dependent ligation of histidine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (His-AMP). Plays a role in axon guidance.
References:
1. Abbott, JA. et al. (2018) Human mutation 39, 415-432. PMID: 29235198
2. Safka Brozkova, D. et al. (2015) Brain : a journal of neurology 138, 2161-72. PMID: 26072516
Note: For research use only.