Anti-Human GFRA4 Antibody (SAA1900)

Description: Anti-Human GFRA4 Antibody (SAA1900) [SAA1900] (RA12544) is a mouse monoclonal antibody detecting GFRA4 in ELISA. Suitable for Human.
Host species: Mouse
Isotype: IgG2a, kappa
Species reactivity: Human
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA
Target: GDNF family receptor alpha-4, GDNFR-alpha-4, GFRA4, GFR-alpha-4, GDNF receptor alpha-4, Persephin receptor
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: GDNF family receptor alpha-4 (GFRA4) is a ~31 kDa protein. Receptor for persephin (PSPN), a growth factor that exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons. Acts by binding to its coreceptor, GFRA4, leading to autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla.
References:
1. Lindahl, M. et al. (2001) The Journal of biological chemistry 276, 9344-51. PMID: 11116144
Note: For research use only.