Anti-Human CD307a/FCRL1/IRTA5 Antibody (SAA1941)

Description: Anti-Human CD307a/FCRL1/IRTA5 Antibody (SAA1941) [SAA1941] (RA12585) is a mouse monoclonal antibody detecting CD307a in ELISA. Suitable for Human.
Host species: Mouse
Isotype: IgG2a, kappa
Species reactivity: Human
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA
Target: CD307a, Fc receptor homolog 1, hIFGP1, FcRL1, Fc receptor-like protein 1, FCRL1, IRTA5, IFGP family protein 1, FcR-like protein 1, FcRH1, Immune receptor translocation-associated protein 5, IFGP1, FCRH1
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Fc receptor-like protein 1 (CD307a/FCRL1) is a ~46 kDa protein. Type I transmembrane surface glycoprotein preferentially expressed by B-cells that regulates BCR-mediated signaling responses. Recruits ABL1 as the intracellular effector molecule to enhance B-cell activation. Also plays a negative role by suppressing ERK activation under homeostatic and BCR-stimulated conditions in a GRB2-dependent manner.
References:
1. Leu, CM. et al. (2005) Blood 105, 1121-6. PMID: 15479727
Note: For research use only.