Anti-Human SLC16A3/MCT4 Antibody (SAA1948)

Description: Anti-Human SLC16A3/MCT4 Antibody (SAA1948) [SAA1948] (RA12592) is a mouse monoclonal antibody detecting SLC16A3 in ELISA. Suitable for Human.
Host species: Mouse
Isotype: IgG2a, kappa
Species reactivity: Human
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA
Target: MCT 4, Solute carrier family 16 member 3, SLC16A3, MCT4, Monocarboxylate transporter 4
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Monocarboxylate transporter 4 (SLC16A3/MCT4) is a ~49 kDa protein. Proton-dependent transporter of monocarboxylates such as L-lactate and pyruvate. Plays a predominant role in L-lactate efflux from highly glycolytic cells.
References:
1. Manning Fox, JE. et al. (2000) The Journal of physiology 529 Pt 2, 285-93. PMID: 1110164
2. Sasaki, S. et al. (2013) PloS one 8, e67690. PMID: 23935841
3. Contreras-Baeza, Y. et al. (2019) The Journal of biological chemistry 294, 20135-20147. PMID: 31719150
Note: For research use only.