Anti-Human ANTXR1/TEM8 Antibody (SAA1962)

Description: Anti-Human ANTXR1/TEM8 Antibody (SAA1962) [SAA1962] (RA12606) is a mouse monoclonal antibody detecting ANTXR1 in ELISA. Suitable for Human.
Host species: Mouse
Isotype: IgG2a, kappa
Species reactivity: Human
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA
Target: TEM8, ATR, Anthrax toxin receptor 1, ANTXR1, Tumor endothelial marker 8
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Anthrax toxin receptor 1 (ANTXR1/TEM8) is a ~62 kDa protein. Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton and thereby plays an important role in normal extracellular matrix (ECM) homeostasis. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells. May also act as a receptor for PLAU.
References:
1. Zhang, LC. et al. (2018) Cell communication and signaling : CCS 16, 62. PMID: 30241478
Note: For research use only.