Anti-Human TNFSF15/TL1A Reference Antibody (PRA023)

Description: Anti-Human TNFSF15/TL1A (PRA023) (BS11955) is a research-grade recombinant antibody targeting TNFSF15. Produced in mammalian cells with native-like glycosylation.
Highlights:
• Research Grade — For PK/PD studies, assay development, and ADA research.
• Native Glycosylation — Mammalian expression ensures native-like patterns.
Host species: Human
Isotype: IgG1-kappa
Species reactivity: Human
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 1mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: TNFSF15,Vascularendothelialcellgrowthinhibitor,VEGI,TL1,TNFligand-relatedmolecule1,Tumornecrosisfactorligandsuperfamilymember15
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: PRA023,TNF-likeligand1A
Background: Tumor necrosis factor ligand superfamily member 15 (TNFSF15/TL1A) is a ~28 kDa protein. Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis.
Note: For research use only. Not suitable for clinical or therapeutic use.