Anti-Kir2.2 K+ channel Antibody (N124B/38)

Host species: Mouse
Isotype: IgG2a, kappa
Species reactivity: nan
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: IHC, WB
Target: Inward rectifier K(+) channel Kir2.2v, IRK-2, Inward rectifier K(+) channel Kir2.2, Potassium channel, inwardly rectifying subfamily J member 12, IRK2, KCNJN1, KCNJ12, ATP-sensitive inward rectifier potassium channel 12
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: ATP-sensitive inward rectifier potassium channel 12 (KCNJ12/Kir2.2 K+ channel) is a ~48 kDa protein. Inward rectifying potassium channel that probably participates in controlling the resting membrane potential in electrically excitable cells. It probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Note: For research use only.