Anti-MiRP2 K+ channel Antibody (K81/15)

Description: Anti-MiRP2 K+ channel Antibody (K81/15) [K81/15] (RA13811) is a mouse monoclonal antibody detecting Potassium channel subunit beta MiRP2 in IHC, WB.
Host species: Mouse
Isotype: IgG2a, kappa
Species reactivity: nan
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: IHC, WB
Target: MinK-related peptide 2, Potassium channel subunit beta MiRP2, Potassium voltage-gated channel subfamily E member 3, KCNE3, Minimum potassium ion channel-related peptide 2
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Potassium voltage-gated channel subfamily E member 3 (KCNE3/MiRP2 K+ channel) is a ~11 kDa protein. Ancillary protein that functions as a regulatory subunit of the voltage-gated potassium (Kv) channel complex composed of pore-forming and potassium-conducting alpha subunits and of regulatory beta subunits. KCNE3 beta subunit modulates the gating kinetics and enhances stability of the channel complex. Alters the gating of the delayed rectifier Kv channel containing KCNB1 alpha subunit. Associates with KCNC4/Kv3.4 alpha subunit to form the subthreshold Kv channel in skeletal muscle and to establish the resting membrane potential (RMP) in muscle cells. Association with KCNQ1/KCLQT1 alpha subunit may form the intestinal cAMP-stimulated potassium channel involved in chloride secretion that produces a current with nearly instantaneous activation with a linear current-voltage relationship.
Note: For research use only.